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In phase with the nucleolus
Denis L. J. LafontaineRNA Molecular Biology, Fonds de la Recherche Scientifique (F.R.S./FNRS), Université libre de Bruxelles (ULB), Biopark Campus, B-6041 Gosselies, Belgium
The nucleolus is a biomolecular condensate responsible for ribosome biogenesis. Using super-resolution microscopy, the team of Ling-Ling Chen has identified a novel nucleolar subcompartment, ascribing to it a function in processing the 3′ ends of primary ribosomal RNA transcripts synthesized by RNA polymerase I.