Volume 33, No 7, Jul 2023
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 33 Issue 7, July 2023: 495-496
RNA editing: new roles in feedback and feedforward control
Xiang-Dong Fu*Westlake Laboratory of Life Sciences and Biomedicine, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China
Biological systems use a variety of feedback and feedforward mechanisms to establish and maintain specific cellular programs. In a recent study published in Cell Research, Lin et al. add RNA editing to an S-nitrosylation-induced feedforward process, which, together with another recently reported paradigm of RNA editing-mediated feedback control, implicates a new role of RNA editing in fine-tuning biological outputs.